(A)–(II); (B)–(III); (C)–(IV); (D)–(I)
VLDL transports endogenously synthesized triacylglycerols, chylomicrons move dietary triacylglycerol to tissues, HDL transports cholesterol from periphery to liver, and LDL delivers cholesterol from liver to tissues. The correct option is (B): (A)–(IV); (B)–(III); (C)–(I); (D)–(II).
Question Breakdown
This matching question evaluates lipoprotein functions in lipid transport, crucial for biochemistry in NEET/GATE Life Sciences exams.
Individual Matches
A. VLDL → IV. Transport of endogenously synthesized triacylglycerols
VLDL, produced by liver, carries liver-synthesized triglycerides to peripheral tissues.
B. Chylomicrons → III. Movement of dietary triacylglycerol to various tissues
Chylomicrons, from intestinal cells, transport dietary fats absorbed from meals.
C. HDL → I. Transport cholesterol from peripheral tissues to liver
HDL performs reverse cholesterol transport, removing excess cholesterol from tissues.
D. LDL → II. Transport cholesterol from liver to other tissues
LDL delivers cholesterol from liver to cells for membrane synthesis and hormones.
Option Evaluation
| Option |
A-VLDL |
B-Chylo |
C-HDL |
D-LDL |
Validity |
Reason |
| First |
III |
IV |
I |
II |
False |
A/VLDL ≠ dietary; B/Chylo ≠ endogenous. |
| Second |
IV |
III |
I |
II |
True |
Perfect match: endogenous (VLDL), dietary (Chylo), reverse (HDL), forward (LDL). |
| Third |
I |
II |
III |
IV |
False |
All mismatched (HDL ≠ peripheral cholesterol delivery). |
| Fourth |
II |
III |
IV |
I |
False |
HDL/LDL reversed; ignores triacylglycerol roles. |
Lipoprotein transport pathways—VLDL endogenous triacylglycerols, chylomicrons dietary triacylglycerol, HDL from peripheral tissues to liver, LDL from liver to tissues—are high-yield for competitive exams distinguishing exogenous vs endogenous lipid movement.
Lipoprotein Functions Table
| Lipoprotein (List I) |
Function (List II) |
Origin |
Primary Lipid |
| A. VLDL |
IV. Endogenous triacylglycerols |
Liver |
Triglycerides |
| B. Chylomicrons |
III. Dietary triacylglycerol |
Intestine |
Dietary TG |
| C. HDL |
I. Cholesterol periphery → liver |
Liver/Intestine |
Cholesterol |
| D. LDL |
II. Cholesterol liver → tissues |
VLDL metabolism |
Cholesterol |
Exam Strategy
Remember: Chylo = dietary (exogenous), VLDL = liver-made (endogenous), HDL = “good” reverse transport, LDL = “bad” delivery. Common error: Swapping HDL/LDL directions.