Q.83 Escherichia coli growing under favorable conditions doubles in every 20 minutes. If the initial number of Escherichia coli cells is 100, what will be the logarithmic number of cells at 17th generation? (Answer up to 1 decimal place)

Q.83 Escherichia coli growing under favorable conditions doubles in every 20 minutes.
If the initial number of Escherichia coli cells is 100, what will be the logarithmic
number of cells at 17th generation? (Answer up to 1 decimal place)

Escherichia coli doubles every 20 minutes starting from 100 cells, reaching 13,107,200 cells after 17 generations. The logarithmic number (base-10 log) of cells at this point is 7.1.

Calculation Method

Bacterial growth follows exponential doubling via binary fission, where each generation multiplies the cell count by 2. The formula is N = N₀ × 2ⁿ, with N₀ = 100 (initial cells) and n = 17 (generations). Substituting gives
N = 100 × 2¹⁷ = 100 × 131072 = 13,107,200 cells.

The logarithmic number means log₁₀(N). Compute log₁₀(13,107,200) = log₁₀(100) + log₁₀(2¹⁷) = 2 + 17 × log₁₀(2) ≈ 2 + 17 × 0.3010 = 7.117, rounded to 7.1.

Step-by-Step Generations

Track key milestones to verify:

Generation Cell Count Formula Total Cells
0 100 × 2⁰ 100
10 100 × 2¹⁰ 102,400
17 100 × 2¹⁷ 13,107,200

Each step confirms doubling every generation under the 20-minute condition.

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Introduction

Escherichia coli growing under favorable conditions doubles every 20 minutes, a key concept in microbial growth for CSIR NET life sciences. Starting with 100 initial Escherichia coli cells, find the logarithmic number of cells at the 17th generation (up to 1 decimal place). This exponential growth problem uses N = N₀ × 2ⁿ and log₁₀ for precise calculation.

Understanding Exponential Growth in E. coli

E. coli exhibits logarithmic phase growth via binary fission, doubling populations predictably. With a 20-minute generation time, 17 generations span 17 × 20 = 340 minutes. Initial 100 cells yield 2¹⁷ = 131,072 doublings, totaling 13,107,200 cells.

Detailed Log Calculation

Apply log₁₀(N) = log₁₀(100 × 2¹⁷) = 2 + 17 log₁₀(2). Since log₁₀(2) ≈ 0.3010, 17 × 0.3010 = 5.117, so 2 + 5.117 = 7.117 ≈ 7.1. This matches bacterial growth formulas in textbooks.

CSIR NET Exam Tips

  • Practice similar problems: generation time confirms rapid E. coli proliferation despite DNA replication overlaps.
  • Verify with Python: confirms 7.1 exactly.
  • Common errors include natural log or forgetting base-10 specification.

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