Q.30 Inspiratory Capacity (IC) can be calculated as Tidal Volume (TV) + Inspiratory Reserve Volume (IRV) Tidal Volume (TV) + Expiratory Reserve Volume (ERV) Tidal Volume (TV) − Inspiratory Reserve Volume (IRV) Expiratory Reserve Volume (ERV) − Inspiratory Reserve Volume (IRV)

 Inspiratory Capacity Calculation

Q.29 In the pump Na+ - K+ ATPase during active transport, hydrolysis of ATP provides energy for: 4 mole of Na+ out of cell and 4 mole of K+ into cell 1 mole of Na+ out of cell and 1 mole of K+ into cell 3 mole of Na+ out of cell and 2 mole of K+ into cell 2 mole of Na+ into the cell and 3 mole of K+ out of cell

Na+ K+ ATPase Pump

Q.28 The drug sildenafil (Viagra) works by: 1. Relaxation of smooth muscles and vasodilation by activating geranylyl cyclase 2. Contraction of smooth muscles and vasodilation by activating adenylyl cyclase 3. Relaxation of smooth muscles and vasodilation by inhibiting cGMP phosphodiesterase 4. Contraction of smooth muscles and vasoconstriction by activating cGN'1P phosphodiesterase

Sildenafil Viagra Mechanism

Q.27 Synthesis of 2.3-bisphosphoglycerate increases in high altitude because: 1. 2,3-bisphosphoglycerate favours the relaxed state of haemogobin 2. 2,3-bisphosphoglycerate serves as an energy source at high altitudes 3. 2.3-bisphosphoglycerate stabilizes the T-conformation of haemoglobin. thereby decreasing the oxygen affinity of haemoglobin. making it more available to the peripheral tissues. 4. 2.3-bisphosphoglycerate regulates body temperature

Why 2,3-Bisphosphoglycerate Increases at High Altitude

Q.26 Molarity is defined as No. of moles of solute in 1 liter of solution No. of moles of solute in 1 kg of solvent No. of moles of solvent in 1 kg of solute No. of moles of salt in 1 liter of solvent

Molarity Definition

Q.25 Proteins can be separated electrophoretically on the basis of net acidic and basic charge tlu•ough 1. Isoelectric focusing 2. Differential centrifugation 3. Countercurrent Immunoelectrophoresis 4. Pulse field gel electrophoresis

Proteins Electrophoretic Separation

Q.24 Which compound in red cells is ctucial in determining the oxygen affinity of haemoglobin ? 1. Inositol triphosphate 2. Glyceraldehyde-3-phosphate 3.2, 3- Bisphosphoglycerate 4. Phosphatidyl inositol

Hemoglobin Oxygen Affinity Red Cells

Q.23 Another name for cardio lipin is 1. Phosphatidyl choline 2. Phosphatidyl serine 3. Phosphatidyl inositol 4. Diphosphatidyl glycerol

Cardiolipin Another Name

Q.22 Which ofthe following organelle is pelleted first during sub-cellular fractionation by differential centrifugation at 1000 g for 10 minutes 1. Nuclei 2. Mitochondria 3. Lysosome 4. Endoplasmic reticulum

Organelle Pelleted First 1000g Differential Centrifugation

Q.21 Mass-to-Charge or niz ratio can be measured through 1. Gas chromatography 2. I-TV-vis spectrophotometer 3. Fluorescence spectrophotometer 4. Mass spectrophotometer

Mass-to-Charge Ratio Measured by

Q.20 Cyanide is probably the most potent inhibitor of electron transport chain. It binds to: NADH dehydrogenase ATP synthase Succinate dehydrogenase Fe3+ of cytochrome oxidase

Cyanide Electron Transport Chain Binding

Q.19 Which is not a palt of the cytoskeleton? l. Serpm 2. Tubulin 3. Actm 4. Kelatin

Cytoskeleton Proteins

Q.18 The condition fatal infantile mitochondrial myopathy and renal dysfunction involves I. Presence of fumarate 2. Absence of most oxidoreductases of respiratory chain 3. Presence of most oxidoreductases of respiratory chain 4. Absence of succinate

Fatal Infantile Mitochondrial Myopathy

Q.17 Niemann-Pick disease is caused due to a genetic deficiency of β-Galactosidase Ceramidase Sphingomyelinase α-Galactosidase

Niemann-Pick Disease Sphingomyelinase Deficiency

Q.16 A 20 year old boy was advised a liver function test by the doctor upon complaining of pain in the abdominal region and yellowing of nails. Subsequently he was diagnosed of hepatic jaundice. Wllich of the following would you expect in his test repott ? 1. Increased activity of ALT and AST 2. Only increased activity of ALP 3. Only increased activity of AST 4. Only increased activity of ALT

Hepatic Jaundice LFT

Q.15 Creatinine is used to assess the renal glomerular functions because l. Creatinine is easy to estimate 2. The value of creatinine clearance is close to GFR 3. The excretion of creatinine is not constant 4. All of the above

Creatinine Renal Glomerular Function

Q.14 Prostaglandins are synthesized in vivo from the 20-carbon polyunsaturated fatty acid I. Oleic acid 2. Arachidonic acid 3. Cervonic acid 4. Linoleic acid

Prostaglandins Synthesized

Q.13 Which of the following additives need to be added to the blood sample to prepare serum for any clinical analysis? l. Citrate 2. Oxalate 3. EDTA 4. No additives are required

Blood Serum Preparation Additives

Q.12 A person having a BMI of 35 will be categorized as 1. Healthy 2. Grade I obesity/ overweight 3. Grade II Clinical obesity 4. Grade III/Morbid Obesity

BMI 35 Category

Q.11 Cellulose is an unbranched polymer of glucose residues joined by α-1, 4 linkage α-1, 6 linkage β-1, 4 linkage β-1, 6 linkage

Cellulose Unbranched Polymer of Glucose

Q.10 Water can dissolve many organic molecules due to 1. Dipolar character and ability to form hydrogen bond 2. Hydrophilic character and high conductance 3. Amphiphilic character and high insultation capacity 4. Hydrophobic character and ability to fonn disulfide bond

Water Dissolves Organic Molecules

Q.9 Which of the following parameter is used to assess the rise in insulin following consumption of any food 1. PDCAAS 2. Nitrogen balance 3. Glycemic Index 4. Glycogen Index

Parameter Used to Assess Rise

Q.8 Biological value of proteins can be defined as – BV = (Nitrogen retained / Nitrogen absorbed) × 100 BV = (Nitrogen retained / Nitrogen ingested) × 100 BV = Nitrogen retained / (Nitrogen absorbed − Nitrogen retained) × 100 BV = (Nitrogen absorbed / Nitrogen ingested) × 100

Biological Value of Proteins Formula

Q.7 Which of the following is the biologically active fomi of vitamin-D that regulates calciam levels in the kidney and bones? l. 7-dehydrocholesterol 2.24, 25-dihydroxycholecalciferol 3. I-a-25- dihydroxycholecalciferol 4. Cholecalciferol

Biologically Active Form

Q.6 Enantiomers are special type of stereoisomers that are: l. isobars of each other 2. isotopes of each other 3. Not the minor image of each other 4. Minor image of each other

 Enantiomers Are Special Type

Q.5 Oxidases act as l. Use oxygen as an electron acceptor but donot incorporate it into the substrate. 2. Directly incorporate oxygen into the substrate 3. Use H2O2 as an electron acceptor 4. Use molecules other than oxygen (eg : NAD¯) as an electron acceptor

Oxidases Act As

Q.4 Which of the following statement is con•ect about enzyme? 1. A bio catalyst that increases the rate of chemical reaction 2. A biocatalyst that inhibit the rate of chemical reaction 3. Non specific in nature 4. All enzymes are proteinacious in nature

orrect Statement About Enzyme

Q.3 Type IV- delayed hypersensitivity is not caused by I. Macrophage 2. Lymphokines 3. Circulating antibodies 4. T- cells

Type IV Delayed Hypersensitivity Not Caused By

Q.2 Diisopropyl phosphofluoridate (DIPF) act as: 1. Inhibitor of enzymes with serine at active site 2. A type of irreversible inhibitor 3. Reduces the synthesis of prostaglandin 4. Mechanism based inhibitor

Diisopropyl Phosphofluoridate

Q.1 Identify the conect statement about Homotropic. 1. For regulatory enzymes substrate and modulator are identical 2. Modulator is a molecule other than substrate 3. Less- active enzyme 4. Active enzyme substrate complex

Homotropic Enzymes

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