Tag: GATE Biotechnology Previous Year Papers with Solutions

Q.11 A protein is phosphorylated at a serine residue. A phosphomimic mutant of the protein can be generated by substituting that serine with (A) glycine (B) alanine (C) aspartate (D) […]

Q.10 Choose the correct signal transduction pathway. (A) Hormone → 7 TM receptor → G protein → cAMP → PKA (B) Hormone → G protein → 7 TM receptor → […]

Q.9 Heat inactivation of serum is done to inactivate (A) prions (B) mycoplasma (C) complement (D) pathogenic bacteria Heat inactivation of serum at 56°C for 30 minutes primarily inactivates complement […]

Q.8 Nude mice refers to (A) mice without skin (B) mice without thymus (C) knockout mice (D) transgenic mice Nude mice are immunodeficient strains characterized by the absence of a […]

Q.7 Dimethyl sulfoxide (DMSO) is used as a cryopreservant for mammalian cell cultures because (A) it is an organic solvent (B) it easily penetrates cells (C) it protects cells by […]

Q.6 A humanized antibody is one in which the (A) heavy and light chains are from human (B) heavy chain is from human and light chain is from mouse (C) […]

Q.5 B-lymphocytes originate from the bone marrow whereas T-lymphocytes originate from (A) thymus (B) bone marrow (C) spleen (D) liver B-lymphocytes originate in bone marrow, while T-lymphocytes originate from bone […]

Q.4 Identification of blood groups involves (A) precipitation (B) neutralization (C) opsonization (D) agglutination Blood group identification relies on agglutination, where antibodies cause clumping of red blood cells bearing matching […]

Q.3 Idiotypic determinants of an antibody are associated with the (A) constant region of the heavy chains (B) constant region of the light chains (C) variable region (D) constant regions […]

Q.2 The basis for blue-white screening with pUC vectors is (A) intraallelic complementation (B) intergenic complementation (C) intragenic suppression (D) extragenic suppression Blue-white screening in pUC vectors relies on intraallelic […]