77. The pedigree given below represents the genotype at four different loci for the children in generation III. Which one of the given genotypes is likely to represent the genotype […]
Tag: CSIR NET Life Science Previous Year Questions and Solution Genetics
Tag: CSIR NET Life Science Previous Year Questions and Solution Genetics
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X‑Linked STR Loci Pedigree Problem
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- December 3, 2025
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76. In the following pedigree three STR loci A, B and C are linked on the long arm of the X-chromosome in the order centromere-A-B-C-telomere. Further in the table, the […]
Identifying Parents Using Autosomal SNP, STR, mtDNA SNP, and Y‑STR Markers
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- December 3, 2025
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75. Polymorphic DNA sequences are used for molecular identification. Short tandem repeats (STRS) and Single Nucleotide Polymorphism (SNPs) are used as polymorphic markers. The table below summarizes the status of […]
Germline Mutation Analysis in a Family Pedigree Using DNA Sequence Variation and RFLP
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- December 3, 2025
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The following represents sequences of different alleles of a gene found in family represented by mother, (allele1/ allele2), father (allele1/allele 2) and their two sons: Son1 (allele1/allele 2) and Son […]
Microsatellite DNA Fingerprinting
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- December 3, 2025
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73. Microsatellite are used as marker for identifying individuals via DNA fingerprinting os the alleles may differ in the number of repeals. From the Southern blot shown below identify the […]
Late-onset autosomal dominant pedigree analysis with RFLP
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- December 3, 2025
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72. The pedigree given below follows the inheritance pattern of a late-onset (after age of 30 years) genetic disease that is 100% penetrant. Affected individuals are indicated by a solid […]
Microsatellite Marker Linkage Analysis
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- December 3, 2025
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71. An analysis of four microsatellite markers was carried out in a family showing a genetic disorder. The results are summarized below Based on the above, which ot the markers […]
Sickle Cell Anemia Restriction Digest Problem
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- December 3, 2025
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70. Sickle cell anemia is a recessive genetic disease caused due to a point mutation in the 6th codon abolishing one of the MspIIendonuclease digestion site present in the ß-globin […]
RFLP Analysis of β‑Globin MstII Sites
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- December 3, 2025
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69. In normal individuals, there are three Mstll restrictionsites. two flanking the ß-globin gene and one within thegene. In individuals affected by a disease, a singlenucleotide polymorphism in the ß-globin […]
DNA Marker Gel
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- December 3, 2025
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68. The following picture represents a gel profile of a pair of DNA markers observed P1 and P2, their F1 progeny and F2 progeny. Four different profiles were observed in […]


