Tag: CELL SIGNALING

36. Which one of the following is not a G-protein coupled receptor? (1) Epinephrine receptor (2) Transferrin receptor (3) Glucagon receptor (4) Thyroid stimulating hormone receptor   Introduction: G-protein coupled […]

35. Although a majority of G protein-coupled receptors (GPCRs) act through adenylyl cyclase, many of them (GPCR) exert their effects by activating the plasma membrane-bound enzyme phospholipase C-β (PLC-β). These […]

34. The cycling of monomeric G proteins, such as Ras, between active and inactive states is aided by accessory proteins that bind to the G protein and regulate its activity. […]

33. G protein-coupled receptors (GPCRs) are used to detect and respond to many different types of signals, including neurotransmitters, hormones involved in glycogen and fat metabolism and even photons of […]

32. The signal transduction pathway involved in glycogen metabolism triggered in the liver by the hormone epinephrine involves the following steps: (A) Activation of G protein (Gαβγ) by the activated […]

31. Glucose is mobilized in muscle when epinephrine activates Gas. In an experiment in which muscle cells were stimulated with epinephrine, glucose mobilization was observed even after withdrawal of epinephrine. […]

30. In cells having G protein coupled receptor, inhibition of protein kinase A by siRNA technology led to diminished transcription of androgen binding protein (ABP) and CREB protein. Addition of […]

29. G-protein coupled receptors (GPCR) consist of three protein subunits  α, β and γ. In unstimulated state, a- subunit is GDP bound and GPCR is inactive. When GPCR gets activated. […]

28. Which one of the following events NEVER activates the G-protein coupled receptor for sequestering Ca2+ release? (1) Interaction of bind in to sperm receptors. (2) Activation of Frizzled by […]

27. Which one of the following statements about receptor – enzyme isFALSE? (1) A receptor enzyme has an extracellular ligand binding domain, a transmembrane domain and an intracellular catalytic (enzyme) […]