Q.27 Assuming independent assortment and no recombination, the number of different
combinations of maternal and paternal chromosomes in gametes of an organism
with a diploid number of 12 is _________________.
Number of Gamete Combinations for Diploid 12
Diploid number of 12 means 6 pairs of homologous chromosomes, so under independent assortment with no recombination, gametes form 26=64 unique combinations of maternal and paternal chromosomes.
Correct Answer
The number is 64. Fill-in-the-blank: 64
Explanation
Independent assortment occurs during meiosis I, where each homologous pair aligns randomly at the metaphase plate, allowing maternal or paternal chromosomes to segregate independently into gametes. For 2n=12 (n=6 chromosome pairs), no recombination means whole chromosomes assort as units, yielding 2n=26=64 distinct combinations per gamete. This follows Mendel’s second law, maximizing genetic diversity without linkage effects.
Why This Formula?
- Haploid gametes receive one chromosome from each of the 6 pairs.
- Each pair has 2 choices (maternal or paternal), so possibilities multiply: 2×2×2×2×2×2=64.
- No recombination ensures chromosomes stay intact, unlike linked genes.
- Example: For 2n=2 (n=1), 2 gametes; for 2n=4 (n=2), 4 gametes—scales exponentially.


