Q.18 Match the entries in Group I with that in Group II
| Group I | Group II |
|---|---|
| P) Vitamin B1 | 1) Co-enzyme A |
| Q) Vitamin B2 | 2) Flavin mononucleotide |
| R) Vitamin B5 | 3) Pyridoxal phosphate |
| S) Vitamin B6 | 4) Thiamine pyrophosphate |
The correct matching is: P‑4, Q‑2, R‑1, S‑3, so the right option is (A).
Match the entries in Group I with that in Group II
Group I lists four B‑complex vitamins and Group II lists their major coenzyme forms. Understanding each pair helps in biochemistry and CSIR‑NET level questions.
Vitamin B1 and thiamine pyrophosphate
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Vitamin B1 (thiamine) is converted in cells to its active coenzyme form thiamine pyrophosphate (TPP), also called thiamine diphosphate.
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TPP functions as a coenzyme in oxidative decarboxylation of pyruvate and α‑ketoglutarate and in transketolase reactions, making the correct match P‑4 (Vitamin B1 – Thiamine pyrophosphate).
Vitamin B2 and flavin mononucleotide
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Vitamin B2 (riboflavin) is phosphorylated by riboflavin kinase to form flavin mononucleotide (FMN).
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FMN, along with FAD, serves as a flavin coenzyme in redox reactions, so the proper pairing is Q‑2 (Vitamin B2 – Flavin mononucleotide).
Vitamin B5 and Coenzyme A
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Vitamin B5 (pantothenic acid) is an essential precursor for the synthesis of Coenzyme A (CoA).
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CoA carries acyl groups in metabolism (e.g., acetyl‑CoA), therefore the correct association is R‑1 (Vitamin B5 – Coenzyme A).
Vitamin B6 and pyridoxal phosphate
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Vitamin B6 exists as pyridoxine, pyridoxal and pyridoxamine, which are phosphorylated to form pyridoxal 5′‑phosphate (PLP), also called pyridoxal phosphate.
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PLP acts as a coenzyme in transamination, decarboxylation and other amino‑acid reactions, so the match is S‑3 (Vitamin B6 – Pyridoxal phosphate).
Why other options are incorrect
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Option (B) P‑3, Q‑1, R‑4, S‑2 swaps all coenzymes: B1 does not form PLP, B2 is not part of CoA, B5 is not converted to TPP, and B6 is not FMN.
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Option (C) P‑1, Q‑2, R‑3, S‑4 wrongly links B1 to CoA, B5 to PLP and B6 to TPP, each contradicting their known biochemical roles.
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Option (D) P‑4, Q‑2, R‑1, S‑3 is identical to the correct mapping listed earlier and is therefore the only accurate choice among the options.
SEO‑oriented introduction
Competitive exams often ask candidates to match the entries in Group I with that in Group II vitamin B coenzymes, linking water‑soluble B‑complex vitamins to their active coenzyme forms. Knowing these vitamin–coenzyme pairs not only secures quick marks but also strengthens core understanding of energy metabolism and enzyme catalysis crucial for advanced biochemistry and CSIR‑NET preparation.
