14. Red wine and Red grapes are important source of which anti-tumour agent? (1) Taxol (2) Vincristine (3) Resveratol (4) Bradystanin
  1. Red wine and Red grapes are important source of which anti-tumour agent?

    (1) Taxol                                    (2) Vincristine
    (3) Resveratol                          (4) Bradystanin

    Correct answer: (3) Resveratol

    Red grapes and red wine are well-known dietary sources of the polyphenolic compound resveratrol, which shows antioxidant, anti‑inflammatory and anti‑tumour/chemopreventive activities in experimental models.​

    Option-wise explanation:

    • (1) Taxol

      • Taxol (paclitaxel) is a diterpenoid anti‑cancer drug originally isolated from the bark/needles of yew trees (Taxus species), not from grapes or wine. It stabilizes microtubules and is used in chemotherapy.

    • (2) Vincristine

      • Vincristine is a vinca alkaloid obtained from Catharanthus roseus (Madagascar periwinkle). It interferes with microtubule formation and is used to treat leukemias and other cancers, but it is not present in grapes or wine.

    • (3) Resveratol

      • Resveratrol is a stilbene-type polyphenol found in the skins of red grapes and hence in red wine. It has been widely studied for potential anti‑cancer, cardioprotective and neuroprotective effects, including modulation of apoptosis, cell cycle, inflammation and oxidative stress in tumour cells.​

    • (4) Bradystanin

      • This is not recognized as the classic anti‑tumour agent linked to red grapes or red wine in standard biochemistry.

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