12. Mutation in gene ‘X’ leads to lethality in a haploid organjsm. Which one of the following is best suited to analyse the function of gene ‘X’? (1) Pleiotropic mutants […]
Tag: CSIR NET Life Science Previous Year Questions and Solution Genetics
Tag: CSIR NET Life Science Previous Year Questions and Solution Genetics
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Spontaneity of Mutation in Genetics
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- December 4, 2025
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Spontaneity of mutation means (1) Mutation in absence of exogenous mutagen (2) Mutation directly proportion to presence of mutagen (3) Mutation inversely proportion to presence of mutagen (4) Mutation at […]
How Suppressor Mutations Correct Frameshift Mutations
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10. An insertion of single nucleotide in coding region of gene leads to frameshift mutation and result is formation of nonfunctional protein. Under certain condition second suppressor mutation in another […]
How Intragenic Suppressor Mutations Minimize Frameshift Mutation Effects in DNA Sequences
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- December 4, 2025
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9. Consider the following DNA sequence 5’-ATGGGCATAGACGATATGGTAG-3’. Insertion of G between 3rd and 4th position lead to frameshift mutation and non-functional protein synthesis. Which intragenic suppressor mutation will have minimum […]
Lac Operon Nonsense Mutation Polar Effect
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- December 4, 2025
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8. In a lac operon, a nonsense mutation in the gene encoding beta-galactosidase was found to interfere with the expression of downstream permease and transacetylase genes. Which one of the […]
Effect of Polar Mutation in Bacterial Operons
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7. An bacterial operon contains three structural genes A, B, and C in the same order. If polar mutation occurs in gene B, then the effect in protein would be […]
Silent Mutation
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6. If mutation changes codon in such a way that there is no effect on functioning and sequence of protein. This type of mutation is termed as (1) Silent mutation […]
Substitution Mutation Detection
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5. If substitution is the only possible type of mutation, then which technique would be no more useful for detecting them? (1) DNA sequencing (2) PCR amplification (3) Database searching […]
Frame Shift Mutation Induced by Acridines
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- December 4, 2025
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4. The frame shift mutation is induced by- (1) Nitrous oxide (2) Acradines (3) EMS (4) UV rays Frame shift mutations occur due to insertion or deletion of nucleotides not […]
Point Mutation
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3. Point mutation in which there is deletion or addition of one base pair is termed as (1) Deletion (2) Transition (3) Transversion (4) Frame shift mutation A point mutation […]


