CSIR NET Life Science Previous Year Questions and Solution Genetics Archives - Page 11 of 43 - CSIR NET LIFE SCIENCE COACHING | NTA NET LIFE SCIENCE

33. Three E. coli mutants were isolated which require compound 'A' for their growth. The compounds B, C and D are known to be involved in biosynthetic pathway to A. In order to determine pathway, the mutants were grown in a minimal medium supplemented with ONE OF THE COMPOUNDS, A TO D. The results obtained are summarized below: '+' = Growth on medium 'O' = No growth Which of the following equation represents the biosynthetic pathway of A? (1) BCDA (2) CDBA (3) BDCA (4) ACDB

CSIR NET Life Science Previous Year Questions and Solution on Genetics

Decoding E. coli Mutant Pathways

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December 4, 2025
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33. Three E. coli mutants were isolated which require compound ‘A’ for their growth. The compounds B, C and D are known to be involved in biosynthetic pathway to A. […]

Two new chemical compounds X and Y are synthesized in a laboratory and tested for their potency as a mutagen, The nature of the mutation produced by these compounds is tested for reversal by other known mutagens and the following results were obtained: Reversed by new compounds 5-Bromo uracil EMS Hydroxyl amine Acridine orange X Yes Yes No No Y No No No Yes Which statement best describes the nature of the two mutagens? (1) Compound X produces single base substitutions that generate CG to TA transitions and Compound Y produces insertions or deletions (2) Compound X produces insertions or deletions and Compound Y produces single base substitutions that generate CG to TA transitions. (3) Compound X produces single base substitutions that generate CG to TA transitions and Compound Y produces TA to GC transitions. (4) Compound X produces single base substitutions that generate insertions and Compound Y produces deletions.

CSIR NET Life Science Previous Year Questions and Solution on Genetics

Mutagenic Action of Compounds X and Y Explained

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December 4, 2025
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Two new chemical compounds X and Y are synthesized in a laboratory and tested for their potency as a mutagen, The nature of the mutation produced by these compounds is […]

31. A scientist synthesized four new chemicals which had mutagenic potential and named then as Cl, C2, C3 and C4. He tried to analyse the nature of mutations caused by them and obtained the following results: Which one of the following answers describes the mutagenic potential of the chemicals? (1) C1 causes transitions, C2 causes transversions or large deletions, C3 causes transitions and C4 causes single base insertions or deletions (2) C1 causes transversions, C2 causes transitions, C3 causes transversions and C4 causes large deletions (3) Cl cause large deletions, C2 causes transitions, C3 causes transversions and C4 causes single base insertions (4) Cl and C3 causes transversions while C2 and C4 causes transitions

CSIR NET Life Science Previous Year Questions and Solution on Genetics

Mutagenic Potential of Chemicals C1, C2, C3 and C4

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December 4, 2025
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31. A scientist synthesized four new chemicals which had mutagenic potential and named then as Cl, C2, C3 and C4. He tried to analyse the nature of mutations caused by […]

30, A chemist synthesizes three new chemical compounds in the laboratory and names them as X, Y and Z. After analyzing mutagenic potential of all these compounds, the geneticist observed that all are highly mutagenic. The geneticist also tested the potential of mutations induced by these compounds to be reversed by other known mutagens and obtamed the following results Mutation produce by Reversed by Nitrous acid Hydroxyl amine Acridine orange X YES SOME NO Y NO NO NO Z NO NO YES Assumjng that X, Y and Z caused any of the three types of mutations, transition, transversion or single base deletion, what conclusions can you make about the nature of mutations produced by these compounds? (1) X causes transversion; Y causes transition; Z causes single base deletion (2) X causes transition; Y causes transversion; Z causes single base deletion (3) X causes transition; Y causes single base deletion; Z causes transversion (4) X causes transversion; Y causes single base deletion; Z causes transition Mutations produced by Mutation Reversed by 2-amino purine Nitrous Acid Hydroxyl amine Acridine orange C1 YES YES SOME NO C2 NO NO NO NO C3 YES YES NO NO Mutation produce by Reversed by Nitrous acid Hydroxyl amine Acridine orange X YES SOME NO Y NO NO NO Z NO NO YES Assumjng that X, Y and Z caused any of the three types of mutations, transition, transversion or single base deletion, what conclusions can you make about the nature of mutations produced by these compounds? (1) X causes transversion; Y causes transition; Z causes single base deletion (2) X causes transition; Y causes transversion; Z causes single base deletion (3) X causes transition; Y causes single base deletion; Z causes transversion (4) X causes transversion; Y causes single base deletion; Z causes transition

CSIR NET Life Science Previous Year Questions and Solution on Genetics

Nitrous Acid, Hydroxylamine and Acridine Orange with X, Y, Z

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30, A chemist synthesizes three new chemical compounds in the laboratory and names them as X, Y and Z. After analyzing mutagenic potential of all these compounds, the geneticist observed […]

29. A chemist synthesized three new chemical compounds, MI, M2 and M3. The compounds were tested for their mutagenic potential and were found to be highly mutagenic. Tests were made to characterize the nature of mutations by allowing the reversion with other mutagens. The following results were obtained: Mutations produced by Reversed by 2-amino purine Nitrous Acid Hydroxyl amine Acridine orange M1 NO NO NO NO M2 YES YES NO NO M3 NO NO NO YES C4 NO NO NO YES Which one of the following conclusions drawn regarding the nature of mutations by the compounds is correct? (1) M1- transversion, M2 – insertion, M3 –deletion (2) M1- transition, M2- transversion, M3 – insertion (3) M1 – insertion, M2 – transition, M3 – transversion (4) M1 – transversion, M2 – transition, M3 – insertion

CSIR NET Life Science Previous Year Questions and Solution on Genetics

Identifying Transition, Transversion and Insertion Mutations from Reversion Tests

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December 4, 2025
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A chemist synthesized three new chemical compounds, MI, M2 and M3. The compounds were tested for their mutagenic potential and were found to be highly mutagenic. Tests were made to […]

28. Three met E. coli mutant strains were isolated. To study the nature of mutation these mutant strains were treated with mutagens EMS or proflavins and scored for revertants. The results obtained are summarized below: Mutant Strain Mutagen Treatment EMS Proflavin A - + B + - C - - (+ stands for revertants of the original mutants and - stands for no revertants obtained). Based on the above and the typical mutagenic effects of EMS and proflavin, what was the nature of the original mutation in each strain? (1) A-Transversion; B- Insertion or deletion of a single base; C- Deletion of multiple bases (2) A-Transition; B- Transversion; C- Insertion or deletion of a single base (3) A- Insertion or deletion of a single base; B- Transition; C- Deletion of multiple bases (4) A-Transition; B- Insertion or deletion of a multiple bases; C- Transversion

CSIR NET Life Science Previous Year Questions and Solution on Genetics

E. coli Mutation Question on EMS and Proflavin

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December 4, 2025
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Three met E. coli mutant strains were isolated. To study the nature of mutation these mutant strains were treated with mutagens EMS or proflavins and scored for revertants. The results […]

26. The following are some statements made regarding mutations: A. Change of DNA sequence from AGC to ATC in non- coding strand can have a major impact on the protein production. B. Suppressor mutation restores the original phenotype, only when a second mutation occurs at the original site of the mutation. C. Mutation rates remain the same in all organisms. D. Strand slippage during replication is a consequence of loop formation in one strand of DNA. E. Hydroxylamine adds a hydroxyl group only on cytosine. Which one of the following options represents the combination of all INCORRECT statements? (1) A and B (2) B and C (3) C and D (4) D and E

CSIR NET Life Science Previous Year Questions and Solution on Genetics

Mutations Statements

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December 4, 2025
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26. The following are some statements made regarding mutations: A. Change of DNA sequence from AGC to ATC in non- coding strand can have a major impact on the protein […]

25. A protein has Gly at position 28 (wild type). On mutagenesis, a point mutation leads to conversion of Gly to Arg at position 28 (mutant 1). When mutant 1 is further mutagenized, four different point mutants (mutants 2 to 5) were isolated where the Arg at position 28 was mutated to Ile, Thr, Ser or Gly as represented below: Based on the codons given in the table above, which one of the following codons codes for Gly at position 28 of the wild type protein? (1) GGU (2) GGC (3) GGA (4) GGG

CSIR NET Life Science Previous Year Questions and Solution on Genetics

Identifying the Glycine Codon from Mutational Pathways

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December 4, 2025
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25. A protein has Gly at position 28 (wild type). On mutagenesis, a point mutation leads to conversion of Gly to Arg at position 28 (mutant 1). When mutant 1 […]

24. The base analog 2-aminopurine pairs With thymine, and can occasionally pair with cytosine. The type of mutation induced by 2-aminopurine is (1) transversion (2) Transition. (3) deletion (4) nonsense.

CSIR NET Life Science Previous Year Questions and Solution on Genetics

Understanding the Mutation Type Induced by 2-Aminopurine Base Analog

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December 4, 2025
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24. The base analog 2-aminopurine pairs With thymine, and can occasionally pair with cytosine. The type of mutation induced by 2-aminopurine is (1) transversion (2) Transition. (3) deletion (4) nonsense. […]

23. Dearnination of bases is a common chemical event that produces spontaneous mutation. Which one of the following bases will be formed by deamination of 5-methylcytosine? (1) Uracil (2) Thymine (3) Cytosine (4) Guanine

CSIR NET Life Science Previous Year Questions and Solution on Genetics

Deamination of 5-Methylcytosine Produces Thymine

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December 4, 2025
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23. Dearnination of bases is a common chemical event that produces spontaneous mutation. Which one of the following bases will be formed by deamination of 5-methylcytosine? (1) Uracil (2) Thymine […]

Tag: CSIR NET Life Science Previous Year Questions and Solution Genetics

Decoding E. coli Mutant Pathways

Mutagenic Action of Compounds X and Y Explained

Mutagenic Potential of Chemicals C1, C2, C3 and C4

Nitrous Acid, Hydroxylamine and Acridine Orange with X, Y, Z

Identifying Transition, Transversion and Insertion Mutations from Reversion Tests

E. coli Mutation Question on EMS and Proflavin

Mutations Statements

Identifying the Glycine Codon from Mutational Pathways

Understanding the Mutation Type Induced by 2-Aminopurine Base Analog

Deamination of 5-Methylcytosine Produces Thymine

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