Human sperms are allowed to fertilize ova having non- functional ovastacin. The following possibilities may be of significance in the fusion of these gametes: A. The sperms will not fertilize ova. B. The sperms will bind and penetrate the zonapellucida but will not be able to fuse with ovum membrane. C. ZP2 will not be clipped by cortical granule protease. D. CD9 protein of egg membrane microvilli will not be able to interact with sperm membrane proteins in the absence of ovastacin. E. Polyspermy may occur frequently. Which combination of statements represent the outcome of the above event? (1) A and B (2) C and E (3) C and D (4) B and C

How Non-Functional Ovastacin Impacts Polyspermy Prevention in Human Fertilization

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