Q.34 If the rate at which E. coli divides is
0.5 h−1, then its doubling time is ______ h.
Calculate 0.5 h⁻¹ Rate to 1.386 Hours
The doubling time for E. coli at a division rate of 0.5 h⁻¹ is 1.386 hours, derived from the standard formula:
td = ln(2) / k
Here, k is the growth rate constant. This reflects exponential bacterial growth during the log phase, common in microbiology studies. Understanding this calculation aids precise modeling of microbial populations in research or lab settings.
Core Formula Explained
Doubling time td measures the time for a bacterial population to double under exponential growth:
td = ln(2) / k
With ln(2) ≈ 0.693 and k = 0.5 h⁻¹:
td = 0.693 / 0.5 ≈ 1.386 hours
This continuous growth model applies to E. coli in ideal lab conditions, such as nutrient-rich media.
Step-by-Step Calculation
Start with the growth equation:
Nt = N0 ek t
Doubling occurs when Nt = 2 N0, so set t = td:
2 = ek td ⇒ k td = ln(2) ⇒ td = ln(2)/k
Plugging in values:
td = 0.693147 / 0.5 ≈ 1.386 hours
Common Options and Explanations
| Option | Value (hours) | Explanation |
|---|---|---|
| A | 0.5 | Equals the division rate k; confuses rate with doubling time. Inverse relationship overlooked. |
| B | 1.0 | Assumes td = 1/k, which is incorrect for continuous exponential growth; fits only discrete generations. |
| C | 1.386 | Correct: ln(2)/0.5 ≈ 1.386 hours. Standard for exponential bacterial growth. |
| D | 2.0 | Uses log10(2)/k ≈ 0.301/0.5 = 0.602, then miscalculates; base conversion error. |
Only option C matches the precise formula validated across microbiology resources.
Errors in other options stem from mixing discrete (td = 1/k) and continuous growth models.


