52. Vascular endothelial (VE)-cadherin is an important cell adhesion molecule for endothelial cells. Endothelial cells that are unable to express VE-cadherin still can adhere to one another via N-cadherin (neural […]
Tag: Cell-Cell Communication
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Cell-Cell Communication
Role of N-Cadherin in Mesenchymal Condensation and Limb Skeletal Development in Mammalian Embryos
51. Temporal expression of N-cadherin is extremely important during early development of the mammalian embryos. Accordingly, which one of the following statements about N-cadherin is true? (1) Injection of N-cadherin […]
Cell-Cell Communication
Impact of N-Cadherin and N-CAM Mutations on Embryonic Development and Nervous System Formation
Cadherins mediate Ca2+-dependent cell-cell adhesion and play an important role in embryonic development by changing the adhesive properties of cell. Aggregation of nerve cells to form an epithelium is correlated […]
Cell-Cell Communication
Cyclopamine Inhibition of Hedgehog Pathway: Blocking Ci/Gli Transcription Activation in Cells
Preventing the blocking action of Patched protein leads to activation of Cos-2, which dissociates itself from microtubules, activates Ci/Gli which binds to CBP (CREB- binding protein) and promotes transcription of […]
Cell-Cell Communication
Protein Expression Dynamics in Wnt-Activated Signaling Pathways During Embryo Development
48. Which one of the following graphs represents the relative expression of proteins of Wnt-activated signaling cascades involved during development of an embryo? The relative expression of proteins […]
Cell-Cell Communication
Non-Canonical Wnt/PCP Pathway: Key Inducer of Cytoskeletal Changes in Early Development
47. Activation of the Wnt signal transduction pathway is extremely important during early development. Of the various pathways, which one of the following is most likely to induce cytoskeletal changes, […]
Cell-Cell Communication
Signaling Processes NOT Involved in Cellular Movement or Cytoskeletal Changes: Comprehensive Overview
46. Of the following signaling processes which one is NOT involved in cellular movement or cytoskeletal changes? Of the signaling processes involved in cellular movement […]
Cell-Cell Communication
Role of Rho GTPase in Modulating Actin Cytoskeleton in HeLa Cells: Mechanisms and Significance
45. Intracellular transport and cytoskeletal organization of a cell is regulated by nucleotide exchange of different small molecular weight GTPases of Ras super family. Overexpression of which of the following […]
Cell-Cell Communication
Non-Canonical Wnt Signaling Pathway: Role of RhoA and PLC in Cell Polarity and Calcium Signaling
Which of the following is most likely to be activated in the non-canonical Wnt pathway? (1) Disheveled and GSK-3. (2) RhoA and PLC. (3) GSK-3 and RhoA (4) Disheveled and […]
Cell-Cell Communication
Hedgehog Proteins: Key Morphogens in Development and Signaling Pathways
Which one of the following is a group of signalling molecules that act as morphogens during development of an organism and its effects are mediated through the receptor Patched and […]
