(DEC 2008) 2. Enzymes accelerates rate of reaction by (1) Lowering number of transition states (2) Lowering the activation energy of highest transition state (3) Providing direct energy to substrate (4) Providing more chance to substrates to react together

2. Enzymes accelerates rate of reaction by
(1) Lowering number of transition states
(2) Lowering the activation energy of highest transition state
(3) Providing direct energy to substrate
(4) Providing more chance to substrates to react together

The correct answer is:
(2) Lowering the activation energy of highest transition state.

How Enzymes Accelerate Reaction Rates

Enzymes are biological catalysts that increase the rate of chemical reactions by lowering the activation energy required for the reaction to occur. The activation energy is the energy barrier that must be overcome for reactants to transform into products. By stabilizing the transition state and decreasing the activation energy, enzymes enable reactions to proceed much faster at physiological temperatures.

Why Lowering Activation Energy Is Key

  • Activation energy corresponds to the highest energy barrier (transition state) that reactants must surpass for a chemical reaction to happen.

  • Enzymes do not directly provide energy to substrates or simply increase collisions; they specifically stabilize and lower the energy of the transition state.

  • This reduction in energy requirement allows a greater proportion of reactant molecules to participate effectively in the reaction, drastically increasing reaction rate.

Explanation of Other Options

  • (1) Lowering number of transition states: Enzymes do not alter the number of transition states; each reaction pathway has a defined transition state, and enzymes stabilize it.

  • (3) Providing direct energy to substrate: Enzymes do not inject energy into substrates. Their role is to reduce the activation energy barrier, not to supply energy.

  • (4) Providing more chance to substrates to react together: While enzymes can orient substrates to increase the likelihood of reaction, the primary mechanism is lowering the activation energy of the transition state.

How Enzymes Lower Activation Energy

  • Enzymes bind reactants (substrates) at their active site.

  • They may position substrates to favor productive collisions, strain bonds within the substrate, or provide an optimal chemical environment.

  • The enzyme-substrate complex stabilizes the transition state, effectively lowering the energy required for the reaction to proceed.

  • This allows reactions that would otherwise be too slow to sustain life at normal temperatures.

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Enzymes are crucial for speeding up reactions in biological systems, and their fundamental role is lowering the activation energy of the highest transition state during catalysis. This mechanism ensures efficient biochemical processes without altering the equilibrium or directly supplying energy, making life possible at mild temperatures.

58 Comments
  • vishal
    September 12, 2025

    🙏

  • Roopal Sharma
    September 12, 2025

    Enzymes accelerate the reaction by lowering the activation energy .

  • Sakshi yadav
    September 12, 2025

    Enzyme accelerates rate of reaction by lowering the activation energy of highest transition state.

  • Aakansha sharma Sharma
    September 12, 2025

    Lowering the activation energy of highest transition state.

  • Priya dhakad
    September 12, 2025

    Enzymes accelerate rate of rxn by Lowering the activation energy of highest transition state.

  • Mohd juber Ali
    September 12, 2025

    Enzym speed up or accelerate biochamical rexn by lowring activation energy of highest transition site

  • Sakshi Kanwar
    September 12, 2025

    At higher transition state that is at ES complex the enzyme lower the activation energy

  • Heena Mahlawat
    September 12, 2025

    By lowering the energy of highest transition state or by decreasing activation energy needed to begin chemical reaction

  • Mansukh Kapoor
    September 12, 2025

    The correct answer is option 2nd
    By lowering the activation energy of the highest transition state

    • Neha Yadav
      September 12, 2025

      Enzyme accelerates the rate of reaction by lowering the activation energy of highest transition state ( i.e, ES Complex)

  • Varsha Tatla
    September 12, 2025

    Enzyme accelerate the reaction by lowering the activation energy of transition state

  • Aafreen Khan
    September 12, 2025

    Lowering the activation energy of highest transition state

  • Tanvi Panwar
    September 12, 2025

    Enzymes accelerates rate of reaction by lowering activation energy of highest transition state.

  • Dharmpal Swami
    September 12, 2025

    Enzyme accelerate the rate of rex.and lowering the energy of high transition state

  • Santosh Saini
    September 12, 2025

    Enzymes accelerate the rate of a chemical reaction by lowering the activation energy of highest transition state

  • Kanica Sunwalka
    September 12, 2025

    Enzymes- primary mechanism is to lower the Ea of highest transition state
    they do not play role in
    *alteration of transition state
    * injecting energy into substrate

  • Anurag Giri
    September 13, 2025

    Option 2 is correct
    Enzymes are biological catalysts that increase the rate of chemical reactions by lowering the activation energy

  • Kirti Agarwal
    September 13, 2025

    Lowering the activation energy to highest transition state

  • Bharti yadav
    September 13, 2025

    Enzymes accelerate the rate of reaction by Lowering the activation energy of highest transition state.

  • Bhawna Choudhary
    September 13, 2025

    Lowering the activation energy to highest transition state

  • Soniya Shekhawat
    September 13, 2025

    Enzyme is a Bio catalyst that will be that increase chemical reaction by decreasing the activation energy , activation energy means as a energy barrier that means in which prevent to the conversion of reactant and into product so enzyme stabilize the transitions state that will be have decrease the activation energy so reaction is easily processed.

  • Nilofar Khan
    September 13, 2025

    correct answer is (2)
    Lowering the activation energy of highest transition state.

  • Sonam Saini
    September 13, 2025

    Lowering activation energy of highest transistor state

  • Manisha choudhary
    September 13, 2025

    Done sir
    Enzyme reaction ki activation energy ko km kr deti h and transition state ko stablized krte h jis s low temperature p bhi efficiently reaction hoti h
    Enzyme, substrate ko orient kr k bhi rate of reaction bdhata h pr primarily function lowering the activation energy hoti h

  • Ayush Dubey
    September 13, 2025

    Lowering the activation energy of highest transition state

  • Surendra Doodi
    September 14, 2025

    The activation energy is the energy barrier that must be overcome for reactants to transform into products

  • Deepika sheoran
    September 14, 2025

    Option 2nd correct
    Lowering the Activation energy of highest transition state..

  • Pratibha Jain
    September 14, 2025

    correct answer is option (2)
    Lowering the activation energy of highest transition state.

  • Avni
    September 14, 2025

    lowering the activation energy of the highest transition state

  • Khushi Agarwal
    September 14, 2025

    Option B is correct
    Enzymes accelerates rate of reaction by
    Lowering the activation energy of highest transition state

  • Vanshika Sharma
    September 14, 2025

    Enzyme accelerats rate of reaction by lowering the activation energy of higher transition state

  • Anjali
    September 14, 2025

    Lowering the activation energy of highest transition state

  • Simran Saini
    September 14, 2025

    Lowering the activation energy of highest transition state.

  • Varsha Kanwar shishodiya
    September 14, 2025

    Lowering the activation energy of highest transition state.

  • Mitali saini
    September 14, 2025

    The correct answer is:
    (2) Lowering the activation energy of highest transition state.

  • Anju
    September 14, 2025

    Ans:2
    Lowering the activation energy of highest transition state

  • Rishita
    September 14, 2025

    Lowering the activation energy of highest transition state.

  • Arushi Saini
    September 14, 2025

    Enzymes lowers the activation energy of highest transition state

  • Asha Gurzzar
    September 14, 2025

    Lower the activation energy of highest transition state

  • Pallavi Ghangas
    September 14, 2025

    Lowering activation energy

  • anjani sharma
    September 14, 2025

    Lowering the activation energy of highest transition state.

  • Payal Gaur
    September 14, 2025

    Lowering the activation energy of highest transition state

  • Sneha Kumawat
    September 14, 2025

    Lowering the activation energy of highest transaition state

  • yashika
    September 14, 2025

    Enyme lower East of highest transition state

  • Devika
    September 15, 2025

    Lowering the activation energy of highest transition state

  • Preeti
    September 15, 2025

    lowering the activation energy of highest transition state

  • Khushi Vaishnav
    September 15, 2025

    Lowering the activation energy of highest transition state.

  • Bhavana kankhedia
    September 15, 2025

    Lowering the activation energy of highest transition state.

  • Muskan Yadav
    September 15, 2025

    Lowering the activation energy of highest transition state.

  • Anjana sharma
    September 16, 2025

    Lowering the activation energy of highest transition state.

  • Minal Sethi
    September 16, 2025

    Lowering the activation energy of highest transition state

  • Yogita
    September 16, 2025

    Lowering the activation energy of highest transition state

  • Muskan singodiya
    September 16, 2025

    Lowaring the activation energy of highest transition state

  • Alec
    September 16, 2025

    Lowering the activation energy of highest transition state

  • Monika jangid
    September 16, 2025

    Lowering the highest energy of highest transition state

  • Divya rani
    September 17, 2025

    Enzyme accelerates a reaction by lowering the activation energy of the highest Transition state.

  • Priti khandal
    September 17, 2025

    2 is right

  • Palak Sharma
    September 21, 2025

    Enzymes accelerate the reaction by lowering the activation energy .

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