5. A Rh + ve male marries a Rh-ve female, their progenies will be-
(1) Rh +ve only
(2) Rh -ve only
(3) Can be Rh +ve or –ve
(4) Cannot be predicted
Rh Factor Inheritance: Father Rh+ × Mother Rh–
Basic Genetics
Rh+ allele (R): dominant
Rh– allele (r): recessive
- de>rr = Rh–ve person (must be homozygous recessive)
- de>RR or de>Rr = Rh+ve person
Genotype: de>RR OR de>Rr
de>rr
Case 1: Father RR (Homozygous)
Cross: de>RR × rr
| de>R | |
| de>r | de>Rr |
All children: de>Rr → 100% Rh+
Case 2: Father Rr (Heterozygous)
Cross: de>Rr × rr
| de>R | de>r | |
| de>r | de>Rr | de>rr |
50% de>Rr → Rh+
50% de>rr → Rh–
Depends on father’s unknown genotype


