- Which is not true about TCA cycle
(1) takes place in mitochondrial matrix of eukaryotes
(2) is amphibolic pathway
(3) is linked to glycolysis via pyruvate
(4) there is formation of NADPH and FADHBIO
The tricarboxylic acid (TCA) cycle, also known as the citric acid or Krebs cycle, is a central metabolic pathway that plays a crucial role in energy production and biosynthesis. While several statements about the TCA cycle are true, one of the following is incorrect.
This article analyzes the given statements to identify the false one and explains the correct facts about the TCA cycle.
Statement Analysis
(1) Takes place in mitochondrial matrix of eukaryotes
-
True.
The TCA cycle occurs in the mitochondrial matrix in eukaryotic cells, where enzymes catalyze the oxidation of acetyl-CoA to CO₂ and generate reduced coenzymes NADH and FADH₂.
(2) Is an amphibolic pathway
-
True.
The TCA cycle is amphibolic, meaning it functions in both catabolism (breaking down molecules for energy) and anabolism (providing precursors for biosynthesis). Intermediates are used for amino acid, nucleotide, and lipid synthesis.
(3) Is linked to glycolysis via pyruvate
-
True.
Glycolysis produces pyruvate, which is transported into mitochondria and converted to acetyl-CoA by the pyruvate dehydrogenase complex, linking glycolysis to the TCA cycle.
(4) There is formation of NADPH and FADH
-
False.
The TCA cycle produces NADH and FADH₂, not NADPH or FADH. NADPH is primarily generated by the pentose phosphate pathway and certain other metabolic reactions, not the TCA cycle.
Summary Table
Statement Correctness (1) Takes place in mitochondrial matrix True (2) Is amphibolic pathway True (3) Linked to glycolysis via pyruvate True (4) Formation of NADPH and FADH False
Conclusion
The false statement about the TCA cycle is that it produces NADPH and FADH. Instead, the cycle generates NADH and FADH₂ as energy-rich electron carriers.
Correct answer: (4) there is formation of NADPH and FADH
-
24 Comments
Kirti Agarwal
September 18, 2025Statement 4 is incorrect because by the kreb cycle NADH, FADH2, GTP is proudced
Neha Yadav
September 20, 2025Formation of NADPH and FADH is incorrect about kreb cycle ( formation of NADH ,FADH2 is correct)
Bhawna Choudhary
September 21, 2025formation of NADPH and FADH is incorrect bcz TCA cycle generate NADH , FADH2
Sonal Nagar
September 22, 2025there is formation of NADPH and FADH
(Formation of NADPH and FADH2)
Aafreen Khan
September 23, 2025Formation of NADPH and FADH is incorrect option because Kreb cycle form NADH and FADH2
HIMANI FAUJDAR
September 23, 2025Ans incorrect statement is 4 because in TCA cycle NADH and FADH2 is formed instead of NADPH and FADH2.
Dharmpal Swami
September 23, 2025NADH and FADH2 form in TCA cycle
Anurag Giri
September 23, 2025The TCA cycle produces NADH and FADH₂, not NADPH or FADH. NADPH is primarily generated by the pentose phosphate pathway and certain other metabolic reactions, not the TCA cycle.
Manisha choudhary
September 23, 2025Statement -4 is incorrect
TCA cycle s NADH and FADH2 bnta h
NADPH primarily PPP m bnta h
Pallavi Ghangas
September 23, 2025NADH and FADH₂, not NADPH or FADH
Varsha Tatla
September 27, 2025NADH &NAD not NADPH nd NADP
Aakansha sharma Sharma
September 23, 2025formation of NADPH and FADH is incorrect bcz TCA cycle generate NADH , FADH2
Roopal Sharma
September 24, 2025Statement 4 is incorrect because madh and fadh2 is form .
Heena Mahlawat
September 24, 2025Tca produces NADH and FADH2
Nilofar Khan
September 24, 2025Correct answer: (4) there is formation of NADPH and FADH because TCA cycle produce NADH,FADH2
Deepika sheoran
September 24, 2025TCA cycle produce NADH and FADH2.
Minal Sethi
September 24, 2025NADH and FADH2 is formed
option 4 is incorrect
Soniya Shekhawat
September 25, 2025The TCA cycle produces NADH and FADH₂, not NADPH or FADH.
Mohd juber Ali
September 25, 2025NADH AND FADH2 form in krebcycle and NADPH AND FADH FORM IN PPP NOT IN KREBS CYCLE SO OPTION 4 is false
Muskan singodiya
September 25, 2025Their is formation FADH and NADPH is not correct because tca cycle produce NADH and FADH2
Kavita Choudhary
September 26, 2025Formation of NADH and FADH is incorrect because about TCA cycle formation of NADH and FADH2
Avni
September 26, 2025The TCA cycle produces NADH and FADH₂, not NADPH or FADH.
Arushi Saini
September 27, 2025The false statement about the TCA cycle is that it produces NADPH and FADH. Instead, the cycle generates NADH and FADH₂ as energy-rich electron carriers.
Payal Gaur
September 27, 2025TCA cycle produce NADH and FADH2 not NADPH and FADH