32. In human males, autosomal and sex trisomy mains occurs due to-
(1) Error in meiosis
(2) Non-disjunction of chromosome
(3) Dominant Y chromosome
(4) Faulty Repair mechanism
Option-wise explanation
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Error in meiosis
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Too vague. Trisomy is a very specific kind of meiotic error: failure of chromosomes to separate. Many different “errors in meiosis” exist, but the textbook term for trisomy origin is nondisjunction.
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Non-disjunction of chromosome – correct
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Trisomy occurs when a pair of homologous chromosomes (meiosis I) or sister chromatids (meiosis II) fails to separate, so one gamete gets two copies and the other gets none.
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Fusion of such an n+1 gamete with a normal n gamete produces a 2n+1 zygote (autosomal or sex-chromosome trisomy).
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Dominant Y chromosome
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The Y chromosome carries male-determining genes (like SRY) but is not “dominant” in a way that explains trisomy. It does not cause an extra copy of any chromosome.
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Faulty repair mechanism
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DNA repair defects can cause mutations or structural rearrangements, but numerical chromosome abnormalities like trisomy are specifically due to mis-segregation (nondisjunction), not repair failure.
So, autosomal and sex-chromosome trisomies in human males mainly result from chromosomal non-disjunction (option 2).


