1. The pericytes are found in
    (1) myelin sheath
    (2) surrounding coat of a skeletal muscle fibre,
    (3) blood capillary wall
    (4) lymph capillary wall

     


    Where Are Pericytes Found?

    Pericytes are specialized contractile cells embedded within the basement membrane of blood capillaries and postcapillary venules. They closely wrap around the endothelial cells lining these small vessels throughout the body.

    • They are not found in the myelin sheath, surrounding skeletal muscle fibers, or lining lymph capillaries.

    • Their prominent location around blood capillaries allows them to interact physically and chemically with endothelial cells.


    Functions of Pericytes

    • Regulate capillary blood flow via contractile properties.

    • Maintain capillary stability and vessel integrity.

    • Play a role in angiogenesis by supporting endothelial cell proliferation and migration.

    • Contribute to the blood-brain barrier’s maintenance by interacting with endothelial cells, neurons, and astrocytes.

    • Participate in immune cell regulation and clearance of cellular debris.


    Summary Table

    Location Presence of Pericytes Role
    Myelin sheath No Neural insulation by Schwann cells and oligodendrocytes
    Surrounding skeletal muscle fibers No Muscle contraction by muscle fibers
    Blood capillary wall Yes Regulate blood flow and vessel integrity
    Lymph capillary wall No Specialized for lymph fluid transport and immune surveillance

    Conclusion

    Pericytes are found in the blood capillary wall.
    This location underpins their essential roles in microvascular function and neurovascular unit integrity.

    Thus, the correct answer is:

    (3) Blood capillary wall


    Additional Insights

    Pericyte dysfunction is implicated in diseases such as diabetic retinopathy, stroke, and neurodegenerative disorders due to their vital role in vascular health and the blood-brain barrier.

2 Comments
  • Varsha Tatla
    September 16, 2025

    Pericyte is a basement membrane of blodd capillaries

  • Aakansha sharma Sharma
    September 26, 2025

    Pericyte is a basement membrane of blodd capillaries

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