- A type of regeneration in which the differentiated cells divide, maintaining their differentiated function without dedifferentiation and production of undifferentiated mass, is known as
(1) Epimorphosis
(2) Morphallaxis
(3) Compensatory regeneration
(4) Stem cell mediated regeneration
The type of regeneration where existing differentiated cells proliferate to restore lost tissue without dedifferentiating to a stem-like state or forming a blastema is known as compensatory regeneration.
Key Characteristics of Compensatory Regeneration
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No Dedifferentiation: Differentiated cells retain their specialized functions and do not revert to an undifferentiated or stem cell-like state.
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Cell Division in Mature Cells: Proliferation occurs directly in mature, functioning cells, increasing their numbers to regain tissue mass or organ size.
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Absence of Blastema: Unlike epimorphic regeneration, no undifferentiated cell mass forms.
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Examples: Mammalian liver regeneration after partial hepatectomy is a classic example. Hepatocytes proliferate to restore liver mass without dedifferentiation.
Comparison with Other Regeneration Types
Regeneration Type Differentiated Cell Division Dedifferentiation Blastema Formation Example Organisms Epimorphosis No Yes Yes Salamander limb regeneration Morphallaxis Minimal or none No No Hydra, some flatworms Compensatory Regeneration Yes No No Mammalian liver Stem Cell-Mediated N/A (stem cells involved) N/A N/A Hair follicles, planaria neoblasts
Summary
The regeneration mode involving differentiated cells dividing while maintaining their function, without dedifferentiation or blastema formation, corresponds to compensatory regeneration.
Final Answer:
(3) Compensatory regeneration -
