In a genetic assay, randomly generated fragments of yeast DNA were cloned into a bacterial plasmid containing gene ‘X’ essential for yeast viability on minimal media. The recombinant plasmid was […]
Tag: DNA REPLICATION CSIR NET PYQ
Tag: DNA REPLICATION CSIR NET PYQ
DNA REPLICATION CSIR NET PYQ
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Key Steps in Eukaryotic DNA Replication That Require ATP Hydrolysis
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- June 14, 2025
- 42 Comments
Some of the steps in the process of eukaryotic DNA replication mentioned below require hydrolysis of ATP. (A) Phosphodiester bond formation (B) DNA strand separation by helicase (C) Clamp-loader association […]
What Happens to Sliding Clamp-Loaders After They Load Sliding Clamps Onto DNA?
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- June 14, 2025
- 20 Comments
The high processivity of DNA polymerases during replication is because of their association with proteins called sliding clamps. For loading onto DNA, sliding clamps require sliding clamp-loaders. Which of the […]
Understanding Replication Forks, Bubbles, and DNA Synthesis According to Okazaki
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- June 14, 2025
- 30 Comments
65. The following statements are made on DNA replication: A. Replication fork is a branch point in a replication ‘eye’ or ‘bubble’. B. A replication bubble contains two replication forks. […]
Key Facts About Eukaryotic DNA Replication: Origins, Pulse-Chase Labeling, and Elongation Rates
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- June 14, 2025
- 11 Comments
Following are certain statements related to eukaryotic DNA replication: The genome of multicellular animals contain many potential origins of replication. During early development, when embryos are undergoing rapid cell divisions, […]
Which DNA Replication Statements Are Incorrect? A Comparison of Prokaryotic and Eukaryotic Processes
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- June 14, 2025
- 28 Comments
Given below are few statements related to DNA replication […]
Matching DNA Topoisomerases and Polymerases with Their Specific Activities in DNA Replication
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- June 14, 2025
- 27 Comments
Given below are a set of enzymes in Column A and enzyme activities in Column B.Column A Column B (A) DNA (i) Synthesis of topoisomerase I Okazakifragment (B) DNA (ii) […]
Understanding Leading and Lagging Strand Synthesis in Eukaryotic DNA Replication: The Roles of DNA Polymerase α, ε, and δ
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- June 14, 2025
- 23 Comments
Eukaryotic DNA polymerase a has tightly associated primase activity but moderate processivity. DNA polymerase ϵ and Ꟙ are highly processive but lack primase activity. Given below are four statements about […]
What Distinguishes Telomerase from DNA Polymerase? Key Differences Explained
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- June 14, 2025
- 22 Comments
Telomerase, a protein RNA complex, has special reverse transcriptase activity that completes replication of telomerase during DNA synthesis. Although it has many properties similar to DNA polymerase, some of them […]
Evaluating DNA Replication Statements: Effects of Camptothecin, ORC Regulation, DNA Polymerase III Mutations, and Topoisomerase II Function
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- June 14, 2025
- 12 Comments
The following statements are made With reference to DNA replication: Camptothecin causes intra- strand and jnter-strand crosslinks in DNA, leading to stalling of replication forks. Prevention of re-initiation of DNA […]


