CIRCULAR DICHROISM

CIRCULAR DICHROISM

22.      CIRCULAR DICHROISM

22.1.    Application:-
Estimation of protein and nucleic acid conformation 
Determination of conformational changes due to the interactions of molecules like Protein-protein interactions, Protein-DNA interactions, Protein-Ligand interactions etc.
Determination of the thermodynamics and kinetics of folding and unfolding of proteins and nucleic acids 
Changes in stability to thermal or chemical denaturation 
Secondary structure prediction
Compare two macromolecules or same molecule under different conditions
To confirm the newly purified protein that her it is correctly folded or not.


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